In the ad, the 27-year-old actress, who recently announced she is expecting her second child with husband Brian Austin Green, taps into her animal instincts in a skintight leopard print dress.
And with her smoky eye make-up, luscious waves and feminine curves, she is every inch the jungle goddess as she strikes a pose in a brightly-lit forest.
Animal instincts: Megan Fox, 27, has stars in a new jungle-themed campaign for make-up brand Avon
Sultry: With her smoky eye make-up, luscious waves and feminine curves, she is every inch the jungle goddess
The ad, which bears the tagline: 'Let your instinct take over,' is for Avon's new line of fragrance called Instinct.
Ms Fox hugs a bamboo tree in the image as she poses alongside Brazilian male model Marlon Teixeira.
With her strong eyebrows, pillowy pout and flawless complexion, it's no surprise this isn't the actress's first turn as the face of a cosmetics line.
In 2011, she had a starring role in Giorgio Armani's summer beauty campaign.
Stunning: With her strong eyebrows and flawless complexion, it's no surprise this isn't the actress's first turn as the face of a cosmetics line. In 2011, she starred in a campaign for Giorgio Armani beauty
The Oak Ridge, Tennessee native also put her enviable figure as the face of Emporio Armani's spring/summer underwear collection in 2011.
Ms Fox and her actor husband, 40, have been together since 2004 after meeting on the set of TV show Hop and Faith.
They married in a private ceremony in Maui, Hawaii, in June 2010, and welcomed their first child - a son named Noah - in September 2012.
As the new face of Avon, Ms Fox follows in the footsteps of a long line of celebrities including Milla Jovovich, Fergie, Christy Turlington, Olivia Wilde and Reese Witherspoon.